• Question: what is your best experiment you have done

    Asked by 853tund32 to Ross, Aimee, Gemma, Hussain, Robert on 9 Nov 2015. This question was also asked by 293tund46, chatterbox1.
    • Photo: Hussain Jaffery

      Hussain Jaffery answered on 9 Nov 2015:


      The best experiment I did was when I decided to look at how the skeletons of mice were different form those that were mutants. I did this by dyeing the bones and cartilage and I found lots of differences! I choses this because it was the first time did it and I was just following a recipe, so had no experience.

      These differences will help explain the role of an important protein in helping to prevent bone diseases.

    • Photo: Robert Lees

      Robert Lees answered on 11 Nov 2015:


      For me, there are probably two experiments that stand out.

      The first is when I picked out a single cell from roughly 10 million cells in a piece of mouse brain to go back and look at on the nanometre scale (I could see things that were as small as a cell membrane – 10,000x thinner than a hair) – I used a glowing tag to find the cell and then marked it out with a laser to create a map to get back to it. There is a very long process which involves filling it with metal and glass and using an ELECTRON microscope (like a normal microscope, but you use electrons rather than light).

      The second experiment has to be looking in to a mouse’s brain with a microscope and using glowing tags to watch mitochondria (power stations of the cell) moving around in neurons, while the mouse is alive and happy. This is really advanced technology, so it was really great for me to do it!

      What is your best experiment you’ve done at school?

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